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Science

The surprising reason medicine tends to work better for men than women.

Yet another reason why we need more equality.

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Even the medical field has bias.

Men.

We have it pretty good. Especially when it comes to our health.

Not only do we get to write the health care legislation, but increasingly, we're getting all the good medical treatment.

We can thank lab animals for this — and the researchers who study them.

For a long time, researchers believed that male animals were better for trials of new medicine.

It was widely assumed that hormone cycles in females would screw up the results.

As a result, currently, over 75% of all lab animals are male.

animal research, studies, gender bias, disease

Lab mouse in a surgically gloved hand.

Image by Rama/Wikimedia Commons/CeCILL.

The problem is, when you test primarily on male animals, you're making medicine that's more likely to be effective for, well, men.

According to a report in New Scientist, researcher Natasha Karp and a team from the U.K.'s Wellcome Trust Sanger Institute studied tens of thousands of mice of both sexes. They found that when you switch off genes in male mice, the mice express different traits then when you switch off the same genes in female mice.

If genes express themselves differently depending on the sex of the animal, the researchers found, so do some genetic diseases.

drugs, health, politics, community

Gene therapy: rad as hell.

Photo by National Cancer Institute on Unsplash

The team concluded that "drugs optimized for male animals may be less effective in females, or even cause harm." Of the 10 drugs that were pulled from the market between 1997 and 2001, they explained, eight were riskier for women.

Male animal-bias also means drugs that work better for women might not even make it into testing to begin with.

As with the debate over what constitutes an "essential" health care benefit (according to some hi-larious U.S. senators, mammograms shouldn't), when it comes to "who constitutes a full human," it appears men are the considered default setting, while women are an afterthought.

equal rights, equal representation, experiments, medical advancements

A bearded man looking off into the distance all manly.

Photo by Jakob Owens on Unsplash

It's a pretty sweet gig for us men.

The thing is, women are half of us. We like them.

As fully formed human beings with lives, free will, hopes, dreams, and so on, it'd be nice if medicine worked better on them when they got diseases.

There's been some progress toward making medical experiments more equitable, at least where human subjects are concerned.

Clinical trials (on humans) used to involve pretty much no women. Now most are 30-40% female, though that still means women are underrepresented.

Thanks to efforts of researchers like Karp and her team, we now know we need to extend that progress to the animal kingdom as well.

"Unless there’s a really good reason not to, we should be using both sexes in biomedical research," Karp told New Scientist.

Male animals, she argued, have traits just as particular as female hormone cycles that make them similarly varied from an ideal "norm."

Ultimately, more comprehensive research benefits us all — men and women.

Better studies lead to more effective medicine, which leads to less sickness and sadness all around.

That's the hope anyway.

The animals of both genders who turn out to help us out with this project deserve a hearty "thank you."

If we start with equal treatment, we might finally get some equal treatment.

This article originally appeared on 06.29.17

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equality
Pop Culture

Would we feel differently about our bodies if we didn't watch TV? Science seems to think so.

Researchers set out to study this question — and walked away with some really fascinating new data.

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Television has a way of tuning off... healthy images.

Do we all, instinctively, find the same types of bodies attractive? Or do TV, movies, and pictures in magazines subtly influence what sorts of bodies we're attracted to?

Researchers at Newcastle University in the U.K. set out to study this question — and walked away with some really fascinating new data.

The question they posed: Do people who have limited access to TV have different beauty ideals than those who watch more frequently?

It's hardly a secret that Hollywood prefers thin. A 2003 study published in the American Journal of Public Health found that female characters who have bigger bodies were few and far between on TV at the turn of the last decade. When they did appear, they were less likely to have romantic partners and "less likely to considered attractive."

Things have improved in recent years but only slightly. And popular reality shows like, "The Biggest Loser" continue to sell the idea that weight loss is the ticket to feeling attractive.

It raises the question: Would we feel differently about our bodies if we didn't watch so much TV? Or if we saw more positive portrayals of people with bigger bodies on the air?

It's really hard to study this because there aren't a lot of places left in the world that don't have access to Western media.

entertainment, studies, American media, global affects

Even most dogs have access to American TV these days.

Image via Pixabay.

In order to get good data, you need to talk to people who not only rarely or never watch TV and movies, but who are hardly even exposed to them and the culture they help generate.

American TV and movies — and locally-produced TV and movies that draw inspiration from our TV and movies — are pretty much everywhere by now.

But there are some. And that's where the researchers went.

Country, TV access, body image, women

A map representing Nicaragua in South America.

Image by DaDez/Wikimedia Commons.

Specifically, they went to the east coast of Nicaragua, which is home to a number of remote villages, some of which have no or only partially electricity.

Researchers found a remote village with little TV access and asked participants there to react to various images of women's bodies of different sizes.

pageants, military, culture, BMI

A female Kansas National Guardsman competed in the 2014 Miss America Pageant.

Photo by Staff Sgt. Jessica Barett/Kansas Adjutant General's Department Public Affairs Office.

The subjects were asked to rate each image on a scale of 1 to 5. Their responses were compared with those from an urban area and a similar village that had greater access to broadcast media.

Critically, the two villages chosen were very similar culturally — previous studies have had difficulty separating out media viewing habits from other cultural variables that might account for the difference in how the images were perceived. Standards of beauty vary from culture to culture, including certain cultures that prize fatness (much like the "thin ideal" in the West, this is often similarly harmful to women and girls).

The result? Participants in the village with the least media access preferred bodies with a higher body mass index on average than those in the urban area and more connected village.

There are caveats, of course.

Using BMI to measure normal versus abnormal weight has become increasingly controversial recently. It's also impossible to draw big, sweeping conclusions from a single study.

But it's real data. And it does suggest that perhaps we're not hardwired to find smaller bodies attractive.

scientific data, psychology, university studies, media

Science!

Photo by Amitchell125/Wikimedia Commons.

"Our data strongly suggests that access to televisual media is itself a risk factor for holding thin body ideals, at least for female body shape, in a population who are only just gaining access to television," said Dr. Lynda Boothroyd, senior lecturer in psychology at Durham University and co-leader of the study.

In other words, the more TV we watch, the more we're likely to be attracted to lower-weight bodies. The less TV we watch, the more we're likely to look favorably upon higher-weight bodies.

Most importantly, it's evidence that there's nothing inherently attractive about weighing less, and nothing inherently unattractive about weighing more.

It's just something we made up.

theme parks, globalization, studios, China

A sunny day captured at Hong Kong Disneyland.

Photo (cropped) by PoonKaMing/Wikimedia Commons.

 But the good news is that we can un-make it up.How do we do that? Here's one idea: Let's get more people with more bodies of more shapes and sizes we can get on TV, in movies, and in glossy magazines — giving them real lives, real flaws, real romances, and presenting them, at least every so often, as attractive. Like, you know. Real people.This article originally appeared on 02.26.16

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mental health
Education

Scientists studied the bones of ancient women, and we might need to rethink 'women's work'

Women of the Bronze Age were anything but weak.

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Certainly not the story we've been taught to believe

Think about the illustrations you've seen of men and women of the Bronze Age who lived thousands of years ago.

Perhaps there's one you recall from your elementary school text book — in which men are probably depicted hurling bronze spears and strangling lions with their bare hands, while the women are most likely pictured leading children around, sifting through grapes or weaving tiny reeds into baskets (presumably to hold the fruits of their husbands' labor).

It's an idealized image for some. Men and women, dividing labor according to their relative physical strength. Women did important work, but entirely in the domestic sphere, in part because they were less equipped to handle difficult manual labor. Each gender in their natural place. A comforting image of the way the world is "supposed to be."

And according to new research, it's an image that's totally wrong in a major way.

According to a groundbreaking new study, Bronze Age women were jacked.

body building, science, gender roles, research, history

Bronze Age woman or 1980s champion weightlifter Karyn Marshall? Hard to say.

Photo by Virginia Tehan/Wikimedia Commons.

Armed with a small CT scanner and a group of student guinea pigs, University of Cambridge researchers discovered that the arm bones of Central European women of the era were roughly 30% stronger than those of modern women — and 11% to 16% stronger than those of modern women on the the world champion Cambridge women's crew team, who spend multiple hours a day training to rowing a 60-foot boat as fast as humanly possible.

"This is the first study to actually compare prehistoric female bones to those of living women," explained Alison Macintosh, research fellow at the University of Cambridge and lead author of the study, in a news release.

The paper was published in the open-access journal Science Advances.

Agriculture, it turns out, is hard work. Work that Bronze Age women handled on the reg.

huts, community, agriculture, research, historical studies

Bronze Age huts offer a glimpse into life in Clare, Ireland.

Photo via Angella Streluk/Geograph.uk.

Particularly grinding grain into flour, which requires the use of ludicrously heavy stones.

Based on evidence from societies that still produce bread products this way, the researchers determined the prehistoric women likely spent up to five hours a day pulverizing the edible bits so their villages could actually eat food while the men were derping around trophy hunting hyenas.

"The repetitive arm action of grinding these stones together for hours may have loaded women's arm bones in a similar way to the laborious back-and-forth motion of rowing," Macintosh said.

In addition to grinding grain, researchers speculate ancient ladies got up to a range of other muscle mass-building activities...

...including hauling food for livestock, slaughtering and butchering animals for food, scraping the skin off of dead cows and deadlifting it onto hooks to turn it into leather, and planting and harvesting crops entirely by hand.

And, while punching bears and ceremonially tossing boulders at the sun weren't on the researchers' specific list, it's at least possible the women were doing that too.

"We believe it may be the wide variety of women's work that in part makes it so difficult to identify signatures of any one specific behavior from their bones," Macintosh said.

Study senior author Jay Stock said the results suggest "the rigorous manual labour of women was a crucial driver of early farming economies."

"The research demonstrates what we can learn about the human past through better understanding of human variation today," he added.

If nothing else, the findings should complicate the way we think of "women's work" going back centuries. Since the dawn of time, mankind has had boulders to grind. Animals to wrangle. Big, heavy things to lift, and arm muscles to build. And some woman had do it.

This article originally appeared on 11.29.17

interesting
Science

17 photos of animals that prove there's nothing natural about traditional gender roles

These animals demonstrate the greatness of nature and its stubborn unwillingness to conform to human expectations for the way things "should be."

Image via Pixabay.

We have our eyes on you too.

Traditional gender roles are "natural," goes the common refrain.

Heterosexuality? That's natural too, apparently. Staying one gender your whole life? Definitely natural.

There's only one problem: Nature (and science) beg to disagree.

In reality, male and female animals set up their relationships thousands of different ways in the wild. In many species, males are the primary caretakers of the next generation while females ignore their offspring and mate promiscuously. Even the existence of "male" and "female" as distinct categories is often not so clear in certain species.

Some animals have the ability to change sex to respond to various outside pressures and conditions.

A few can even mate with themselves.

Here are 17 animals that demonstrate the greatness of nature and its stubborn unwillingness to conform to human expectations for the way things "should be."

1. Jacanas

birds, science, nature, incubation

"Mom went out for a pack of cigarettes and never came back."

​Photo by Ozan Kill

Ask any tropical bird out there, and they'll tell you that male jacanas are pretty much the best dads of the bunch. Not only do male jacanas stick around the nest to incubate the eggs and raise their offspring, they even carry them under-wing when they fly.

Meanwhile, female jacanas are ... not exactly super nurturing. After gathering up a harem of nearly half a dozen males and laying her eggs, the female jacana splits in order to fly around, murder the young of rival females, and mate with their former partners.

This is considered charming.

2. Clown fish

species, environment, reefs, fish

Clown fish were invented by Disney/Pixar in 2003.

Photo by Rachel Hisko on Unsplash

Like many species of reef fish, clown fish can, and frequently do, change sex. Unlike most species of reef fish however, all clown fish are born male and are led (in familial groups) by a dominant female.

When she dies, the next-biggest male simply ... becomes female and takes charge of the group.

What you just heard was the sound of a billion other species slapping themselves on the forehead at the same time, wondering why they didn't think of that, realizing it's now too late and that now they'd just be, like, hopping on the trend.

3. African buffalo

leadership, hierarchies, grazing, grasslands

Everyone is getting out there for an afternoon stroll.

Photo by Soerfm/Wikimedia Commons.

Not only are female buffalos are responsible for coordinating the movements of the entire herd — they do it democratically. When it's time to find a new grazing spot, each female takes a turn standing up and gazing in the direction they want to travel, and when they're done, the whole group moves that way.

While status hierarchies exist within herds, the elections are equitable — one cow, one vote.

Change You Can Moo-Lieve in. Make the Grasslands Great Again.

4. Bees

matriarchy, male drones, hive, honey

"Aaaaaaagh! Aaaaaagh! Aaaaaagh!" — Nicholas Cage.

Photo by Aaron Burden on Unsplash

Bees famously take the matriarchy to the extreme. A single queen bee oversees thousands of smaller female workers and male drones.

While most bees live, at most, a few weeks, the queen typically survives several years before the hive goes looking for a new queen to start the cycle over again. All to advance the species-wide goal of refusing to fly out of your car even though all four windows are down.

5. Komodo dragons

komodo dragon, eggs, offspring, evolution

Party out with your tongue out... alone even.

Photo by Mark Dumont/Wikimedia Commons.

Female komodo dragons can lay viable eggs that produce offspring without a male partner, which pretty much explains why komodo dragon Tinder never truly caught on.

6. Praying mantises

copulation, life cycle, insects, hunters

Not as romantic as it looks.

Photo by Oliver Koemmerling/Wikimedia Commons.

Mantis males are often smaller than mantis females, a discrepancy that leaves many males feeling insecure, as it enables females to frequently — though not always — eat their heads during sex.

7. Common reed frogs

amphibians, forrest, frogs, reproduction

So many choices for the day ahead.

Photo by ChriKo/Wikimedia Commons.

These tiny, resilient amphibians can change sex from female to male, allowing them to successfully reproduce if they suddenly find themselves surrounded by frogs of the same sex.

This ability makes them one of the most successful species on Earth at inspiring anxious Sam Neil monologues.

8. South American marmosets

monkeys, jungle, troops, community

"Hey, pa? You ... you wanna ... play catch?"

Photo by Maxim Bilovitskiy/https://en.wikipedia.org/wiki/en:Creative_Commons.

Female marmosets tend not to be terribly interested in their babies. A few weeks after giving birth, they're mostly out of their kids' lives forever.

Marmoset dads, on the other hand, are excellent caretakers, feeding, grooming, and transporting their young as well as coaching Marmoset Little League and always batting their kid cleanup.

9. Spotted hyenas

aggression, dominance, African plains, arid climates

Someone has to lead this party.

Photo via Pixabay.

Not only are female hyenas stronger and more aggressive than males, male and female hyena genitals are nearly identical in appearance. They're so similar that it's extremely difficult to tell the difference with the naked eye, which ultimately doomed the '70s game show "What Sex is That Hyena?" to cancellation after just half a season.

10. Seahorses

eggs, mating process, sea life, oceans

"OK, so. I need a really big favor."

Photo by Mikhail Preobrazhenskiy on Unsplash

While males of numerous species nurture their offspring, the male seahorse takes things several steps further. During the mating process, he receives eggs from the female and not only fertilizes them, but carries the offspring until they hatch.

A recent poll of male seahorses found that an overwhelming majority experience a secret surge of satisfaction when their partners get kidney stones.

11. Cuttlefish

coloration, species rivalries, genetics, fish

Blumph.

Photo by Michal B. on Unsplash

Unlike middle school boys across America, male cuttlefish don't have a lot of hang-ups about appearing feminine to their peers. Masters of camouflage, these future delicious fried antipasto will often alter their coloration in order to pass for female around rival males.

If an actual female is around, they'll leave the other half of their body as is, appearing half male and half female.

12. Topi antelopes

Africa, herd animals, promiscuity, food

Oh hey.

Photo by Whit Welles/Wikimedia Commons.

Female topi antelopes are not only sexually promiscuous, but when it's time to mate, they almost always make the first move. In some cases, female topis pester male antelopes for sex so relentlessly that the male has to physically fight them off. (Cue dozens of Facebook commenters yelling at male antelopes for complaining about something that's "obviously awesome" and insisting they're lucky and should "just be grateful for the attention.")

13. Laysan albatrosses

birds, mating, wildlife

"Al." "Al."

Photo by Patte David/U.S. Fish and Wildlife Service/Public Domain Images.

Some female albatrosses mate in female-female pairs, often for life.

(Side note: All male albatrosses are named Al Batross. Every single one of them. That's a proven fact).

14. Banana slugs

slugs, sex organs, horror

"When I think about you..."

Image via Pixabay.

A hermaphroditic species, banana slugs have both male and female sex organs and occasionally mate with themselves.

Though banana slugs do seem to prefer mating with other slugs, doing so typically ends with one slug chewing the other's penis off, because nature is a cavalcade of endless, random horror.

15. Orcas

whales, pods, matriarchal, peers

"You have to hit the home button twice, grandma."

Photo by Mike Doherty on Unsplash

Killer whales live in matriarchal pods, and female whales are more likely to take charge of the group than their male peers.

The oldest female whales are often the go-to source for information about where to find food, and in exchange for keeping the whole family alive, the younger whales patiently show them time and again how to use the iPad.

16. Emperor penguins

documentaries, Antartica, frozen tundra, trekking

"Where is that voice coming from?"

Photo via Pixabay.

Anyone who's seen "March of the Penguins" knows that male emperor penguins guard their eggs tightly, perilously balancing them on their feet while their female companions go off to do traditional woman stuff like trekking across the Antarctic tundra, diving for food in the freezing cold ocean, and pleading with Morgan Freeman to shut the hell up so they can focus on not being eaten by seals for like five goddamn seconds.

17. Bonobos

genetics, sex, apes, animal kingdom

"Mmmmmm. Yeah. Mmmmm. All right. Yeah." — Bonobos, all the time.

Photo by Sean Foster on Unsplash

The female-led bonobos have invented perhaps the most ingenious way of preventing intra-species violence in the entire animal kingdom. Basically, everyone just has sex with everyone else — males with females, females with females, males with males, in pretty much every kind of way imaginable.

The near-constant hetero-homo-orgiastic delight that results pretty much prevents anyone from being mad at anyone ever and unites the species around the common goal of being the best apes ever invented.

We share about 99% of our DNA with bonobos.

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