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A scientist created a 'utopia' for mice and then they all started dying

The results are fascinating, but are they relevant to humanity?

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How could Mouse Heaven go so terribly wrong?

In 1968 John Calhoun, a scientist and animal behavioralist, decided to create a "utopia" for mice. It would have unlimited food and water, with beautiful nesting spaces and plenty of materials for the mice to make cozy homes with. Sweet experiment! the mice were probably thinking. Much better than the Maybelline trials we're used to.

However, there was a catch, of course. There was one thing the utopia would be lacking, and that would be physical space. As the mouse population grew, overcrowding would become an issue, and Calhoun wanted to study the problems this would potentially cause. That sound you hear is the collective sigh of the disappointed mice who were stoked about the 24/7 all-you-can-eat buffet.

The experiment, dubbed Universe 25, began when Calhoun introduced four mouse "couples" into the utopian complex. A year or so later, it was overrun and the conditions had turned hellish, even though the mice had not run out of food or water.

mouse, mice, animals, science, research, studies"The conditions had turned WHAT?"Giphy

Initially, for just the eight original mice, the square box Calhoun built included 256 nesting boxes (or apartments) stacked on top of one another. Water bottles and food dispensers were located all along the nesting spots, and mice could travel throughout the complex at will via mesh tunnels. The starter mice were also screened for diseases and the population was obviously protected from predators. The climate was controlled and comfortable. Conditions were perfect.

The first mouse pups showed up a little over three months later, with the population of the colony doubling every 55 days. Nineteen months later, there were 2200 mice living inside the box. With such perfect surroundings, the infant mortality rate was practically zero, leading to the rapid rise in numbers.

mice, mouse experiments, scientific research, animal experiments, overpopulationJohn Calhoun poses with his rodents inside the mouse utopia.Yoichi R Okamoto, Public Domain


By month 19, this rodent utopia had become an overcrowded hellscape. Calhoun noticed three alarming trends, in particular.

In short, everything was devolving into chaos and the very society of the mice began to collapse at a rapid rate.

The "Beautiful Ones" and the "Dropouts": Mice have a complex social hierarchy ruled by dominant alpha males. Sam Kean of Science History Institute Museum & Library notes that, in the wild, non-dominant males (the ones who lose macho showdowns) can skip town and start over somewhere else. But in the close quarters of Calhoun's experiment, with nowhere to hide, they were forced to hang around and viciously battle with each other over scraps. Eventually, non-dominant male mice, which Calhoun called the "Beautiful Ones," withdrew from society completely and only ate, slept, and groomed themselves.

Though resources were unlimited, certain aggressive males hoarded them anyway: The alpha males ruled over everything in the once-utopian mouse society. They kept harems of females in the apartments to mate with and fought fiercely to defend their territory. But new waves of hungry young male mice kept coming and coming, and eventually even the most dominant alphas abandoned their posts. This led to more attacks on nursing females, which in turn led to more mothers kicking their pups out of the nest early.

Birth rate declined dramatically: With the non-dominant males giving up completely and focusing on #SelfCare, dominant males too exhausted from endless battles, and females sick and tired of it all (many became asexual hermits by the end), stopped mating and giving birth entirely. Once this happened, the society was doomed. Even with plenty of food still available, cannibalism was rampant.

Calhoun was not shy about drawing parallels between his research and humanity. "I shall largely speak of mice, but my thoughts are on man, on healing, on life and its evolution," he once wrote.


mice, mouse experiments, scientific studies, universe 25, sociology, overpopulationAlpha male mice, anyone? Photo by Kanashi on Unsplash

There are aspects of his wild experiment that certainly sound familiar.

We live in a world with plenty of resources for everyone, but a few select people hoard more than their fair share. When you think of the rodent "apartments," it's hard not to picture densely packed urban environments where people are stacked on top of each other at every turn. Maybe on some level some of us can relate to the “Beautiful Ones” and their urge to not participate in all the ugliness and just sequester and groom themselves. You can make an argument that when the mice stopped having to worry about food and shelter, it removed the element of challenge from their lives and left them lost–like many of us are lucky enough to not have to wonder where our next meal comes from, and maybe that has something to do with our never-ending search for meaning. Some even go so far as to link more people choosing to delay having children, or not have children at all, with the collapsing society of the mice.

But Calhoun's work has also been heavily scrutinized, with some claiming it's based on shaky science. And in the end, there’s the small matter that humans are not mice. We are infinitely more complicated, and so much better suited to adapting to our environments. Kean writes, "Ultimately Calhoun’s work functions like a Rorschach blot—people see what they want to see."

It's fascinating and thought-provoking nonetheless.

You may not have heard of the Ig Nobel Prizes, but they're basically the best thing about science.

They're a parody of the Nobel Prizes and are given out once a year. But these awards don't go to the kinds of studies that'll get anyone a meeting with the president or cure space fever. Instead, the prizes are given out to some of the weirdest, strangest, and just plain funniest academic achievements of the past year.

There are prizes in 10 different categories. Here are this year's winners:


1. The effect of polyester pants on rats' sex lives.

Image via iStock.

The reproduction category was won by the late Ahmed Shafik, of Egypt, for two studies looking at whether polyester, cotton, and wool trousers affected the sex lives of rats and humans.

2. Assessing the perceived personalities of rocks.

Image via iStock.

Are your rocks rugged? Sincere? Excited? These winners of the economics prize can tell you!

3. Why dragonflies love tombstones.

Photo by Vincenzo Pinto/AFP/Getty Images.

Nine scientists won the physics prize together for figuring out why certain dragonflies kept wigging out around polished black tombstones. Turns out the polished grave markers look just like water to the bugs!

The scientists also looked at why white-haired horses were so dang good at shooing away flies.

4. The chemistry prize was given to Volkswagen, for making emissions "disappear."

Photo by Alexander Koerner/Getty Images.

The chemistry prize this year was a little dig at Volkswagen, who cheated automobile emissions testing.

5. What happens if you scratch an itch while looking in a mirror?

Image via iStock.

Five scientists in Germany revealed that if you have an itch on the left side of your body, you can fix it by looking into a mirror and scratching the right side instead! For that they won the medicine prize.

6. Scientists ask lying liars about lying.

Image via iStock.

Scientists asked 1,000 liars about how often and how good they were at lying. Turns out, kids are masters of deception. This won them the psychology prize.

7. "On the Reception of Detection of Pseudo-Profound Bullshit."

Image via iStock.

Turns out some people are just bad at detecting what is and what isn't proactive paradigm-shifting phenomena that'll revolutionize your energy flow. Who knew? This was the winner of the peace category.

8.  For two researchers who learned what it means – what it really means – to be a badger and a goat.

Thomas Thwaites at the prize ceremony. Photo by Michael Dwyer/AP.

The biology category was jointly awarded to two men: Charles Foster, who lived as a badger, otter, deer, fox, and a bird; and Thomas Thwaites, who created an entire prosthetic goat-suit ... to live among the goats.

9. For a three-volume autobiographical work about the pleasure of collecting flies.

Image via iStock.

Specifically both dead flies and "flies that are not yet dead." This was the literature prize.

10. "For investigating whether things look different when you bend over and view them between your legs."

Image via iStock.

The perception prize was given for finding out that doing this might make images appear brighter and more distinct. Wow.

These are hilarious, but it's all in good fun.

Photo by Michael Dwyer/AP.

The winners all have a chance to bow out if they don't want to take part. And if they do want to accept their awards, they're invited to Harvard, where they're greeted with an adoring audience, (real) Nobel laureate emcees, prizes, and even an opera.

Marc Abrahams, who started the prizes, said the prizes are unique because it's not about who's the best or the worst or the most important.

"The only thing that matters is that it makes people laugh and then think," Abrahams said.

And there are a couple things we can take away.

Such as just because something is funny doesn't mean it can't still be helpful (imagine using the itchy mirror trick for a kid with chicken pox or in a burn ward). Or maybe these prizes show that science is still a human endeavor, and humans are, in the end, pretty weird, funny little animals ourselves.

But most of all, Abrahams hopes these can be a kind of inkblot test. People so often get told what's good and bad, but these prizes are so off-the-wall, they kind of defy any pat analysis. Abrahams hopes that each person will end up thinking and deciding for themselves which of these are good, silly, stupid, hilarious, or secretly brilliant.

As for me, I think I'm going to change up my wardrobe and then see what this whole badger thing is about.

"Mirror, mirror, under waves — who's the fairest manta ray?"

Presumably, that's what's on this guy's mind:



GIF via Csilla Ari, Ph.D./New Scientist.

That ray, you see, is circling around a mirror placed in its tank by Csilla Ari, a researcher at the University of South Florida in Tampa.

Ari filmed a pair of these aquatic blanket-creatures on two separate occasions: once with a mirror in their tank and once without. She observed a noticeable difference in the behaviors of these typically antisocial animals in the presence of their own reflections.

They would blow bubbles while facing the mirror, for example, or wave their fins around and swim circles past the looking glass, like in the GIF above. But as fun as it is to spend an afternoon watching fish act funny, this strange little experiment still begged the question: Why would a manta ray care about a mirror?

It turns out, there are actually a few possibilities:

Science fact: Rays love dancing. GIF via Cheezburger.

1. They were just making sure they're not a vampire or monster.

It's a commonly accepted scientific fact that evil mystical folk creatures don't have reflections — and once upon a time, people treated the so-called "devil ray" like monsters. There were stories of these flappy fish using their prodigious size to sink ships, and they gained a (completely fabricated) reputation for attacking humans. They even starred in a couple of monster movies, like "The Sea Bat (1930)" and "Devil Monster (1936)" — though sadly, none of them left their fin-prints on the Hollywood Walk of Fame.

While manta rays can get pretty big — some are more than 20 feet across — they're not actually that dangerous in real life (and they're definitely not demonic).

"Mr. DeMille, I'm ready for my closeup." GIF from "Devil Monster."

2. Or they were checking to see if they had anything in their teeth.

So if manta rays aren't man-eating monsters, what do they eat? It turns out, they're really into those teeny tiny floating plants and animals we call plankton — so basically the opposite of human flesh. In fact, the ray's iconic horns are actually fins on the sides of their head that help them funnel plankton into their mouths!

Nom nom nom nom nom. GIF from GoPro/YouTube.

3. Perhaps they wanted to admire how smart they look.

Manta rays have the biggest brains for their bodies of any fish. There are even some stories of rays coordinating and cooperating with each other (even though they generally keep to themselves).

Intelligence is beautiful, so maybe these rays were just taking in the sights?

Woohoo! We're smart! Let's have a flap party about it! GIF from BBC Earth.

4. They could have also been looking for gray hairs.

The manta ray as we know it today has been around for about 5 million years, and its relatives date back around 20 million years.And they're not just an old family either — individual rays can live to be 50 years old! (Which is, like, really old for a fish.)

"Get off my lawn." GIF via Imgur.

5. Or maybe, just maybe, these manta rays got so excited by the mirror because their advanced intelligence make them self-aware.

The mirror test is a kind-of-vaguely-defined lowest-bar litmus test for determining if animals possess a higher consciousness like humans. The basic idea is that if an animal can recognize itself in a mirror (instead of, say, confusing its own reflection for another member of its species), then that animal must be at least somewhat aware of its own identity.

Other animals that have passed the mirror test include dolphins, chimpanzees, elephants, and magpies. It's only a tentative step, and it may not work for nonvisual animals like octopuses, for example (which lots of us already recognize as a vastly superior alien race). But if the manta rays in the experiment above did actually recognize their own reflections, it would make them the first fish to demonstrate self-awareness.

YAY I'M SELF-AWARE UR SELF-AWARE LET'S BE BFFL.

Of course, we can't exactly prove these manta rays are really as vain as we think they are ... at least, not yet.

But if this research checks out, it has the potential to be an ocean-sized milestone in our larger understanding of consciousness and evolution. Which means we're one step closer to being able to swim up to a manta and say, "Hey, who's that handsome devil ray in the mirror?"

And I think we're all agreed: That would be awesome.